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Napping Increases Risk of Blood Pressure

Have you ever experienced that everything hurts after a sleepless night? A recent study has uncovered a neurotransmitter, N-arachidonoyl dopamine (NADA), linked to the pain caused by sleep deprivation, offering potential avenues for treatment. In sleep-deprived mouse models, researchers found reduced NADA levels in a brain region associated with sensory processing and arousal. Administering NADA to this area effectively alleviated the heightened pain response.

People often nap in between. But is napping good or bad? A new study shows that napping on a regular basis is associated with higher risks for high blood pressure and stroke.

The researchers in China claimed this as the first study to use both observational analysis of participants over a long period of time and Mendelian randomization – a genetic risk validation to investigate whether frequent napping was associated with high blood pressure and ischemic stroke.

The new research is published in Hypertension, an American Heart Association journal.

“These results are especially interesting since millions of people might enjoy a regular, or even daily nap,” says E Wang, Ph.D., M.D., a professor and chair of the Department of Anesthesiology at Xiangya Hospital Central South University, and the study’s corresponding author.

NAPPING; METHOD USED

The information fromUK Biobank  was used for the analysis.  UK Biobank recruited more than 500,000 participants between the ages of 40 and 69 who lived in the United Kingdom between 2006 and 2010. They regularly provided blood, urine and saliva samples, as well as detailed information about their lifestyle. The daytime napping frequency survey occurred 4 times from 2006 – 2019 in a small proportion of UK Biobank participants.

Wang and the team excluded records of people who had already had a stroke or had high blood pressure before the start of the study. This left about 360,000 participants to analyze the association between napping and first-time reports of stroke or high blood pressure, with an average follow-up of about 11 years. Participants were divided into groups based on self-reported napping frequency: “never/rarely,” “sometimes,” or “usually.”

NAPPING; FINDINGS
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