Inhaled MicroplasticsAnd the Threat To Humans

Humans might inhale about 16.2 bits of microplastic every hour, which is equivalent to a credit card over an entire week. A group of researchers point out that inhaled microplasticspose cause serious health risks and the understanding how it travels in the respiratory system is essential for prevention and treatment of respiratory diseases.

In Physics of Fluids, by AIP Publishing, researchers from the University of Technology Sydney, Western Sydney University, Urmia University, Islamic Azad University, the University of Comilla, and Queensland University of Technology developed a computational fluid dynamics model to analyzemicroplastic transport and deposition in the upper airway.

“Millions of tons of these microplastic particles have been found in water, air, and soil. Global microplastic production is surging, and the density of microplastics in the air is increasing significantly,” said author Mohammad S. Islam. “For the first time, in 2022, studies found microplastics deep in human airways, which raises the concern of serious respiratory health hazards.”

THE MOVEMENT OF MICROPLASTICS

The researchers explored the movement of microplastics with different shapes (spherical, tetrahedral, and cylindrical) and sizes (1.6, 2.56, and 5.56 microns) and under slow and fast breathing conditions.

They found that microplastics collect in hot spots in the nasal cavity and oropharynx, or back of the throat.

“The complicated and highly asymmetric anatomical shape of the airway and complex flow behavior in the nasal cavity and oropharynx causes the microplastics to deviate from the flow pathline and deposit in those areas,” said Islam. “The flow speed, particle inertia, and asymmetric anatomy influence the overall deposition and increase the deposition concentration in nasal cavities and the oropharynx area.”

The team note that breathing conditions and size of microplastic influence its overall deposition rate in airways. An increased flow rate led to less deposition, and the largest (5.56 micron) microplastics were deposited in the airways more often than their smaller counterparts.

HELP IN DRUG DELIVERY

The authors believe their study highlights the real concern of exposure to and inhalation of microplastics, particularly in areas with high levels of plastic pollution or industrial activity. They hope the results can help inform targeted drug delivery devices and improve health risk assessment.

“This study emphasizes the need for greater awareness of the presence and potential health impacts of microplastics in the air we breathe,” said author YuanTongGu.

In the future, the researchers plan to analyzemicroplastic transport in a large scale, patient-specific whole lung model that includes environmental parameters such as humidity and temperature.

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