Eating vegetables does not lower risk of cardiovascular disease: study

By 2060, Americans Projected At Higher Cardio Risk

Taking sufficient vegetables helps in maintaining a balanced diet and also in avoiding a wide range of diseases. However, a new study questions if a diet rich in vegetables can lower the risk of cardiovascular disease (CVD).

The researchers from the Nuffield Department of Population Health at the University of Oxford, the Chinese University of Hong Kong, and the University of Bristol says that they found no evidence for this. “That the consumption of vegetables might lower the risk of CVD might at first sight seem plausible, as their ingredients such as carotenoids and alpha-tocopherol have properties that could protect against CVD. But so far, the evidence from previous studies for an overall effect of vegetable consumption on CVD has been inconsistent,”‘a release quoted them.

COOKED/UNCOOKED VEGETABLES

Now, new results from a powerful, large-scale new study in Frontiers in Nutrition shows that a higher consumption of cooked or uncooked vegetables is unlikely to affect the risk of CVD. The study also explained how confounding factors might have explained previous spurious, positive findings.

UK Biobank’s chief scientist and co-author on the study Prof Naomi Allen said, “The UK Biobank is a large-scale prospective study on how genetics and environment contribute to the development of the most common and life-threaten ing diseases. Here we make use of the UK Biobank’s large sample size, long-term follow-up, and detailed information on social and lifestyle factors, to assess reliably the association of vegetable intake with the risk of subsequent CVD.”

ANALYSIS

The UK Biobank, follows the health of half a million adults in the United Kingdom by linking to their health care records. Upon their enrollment in 2006-2010, these volunteers were interviewed about their diet, lifestyle, medical and reproductive history, and other factors.

The risk of dying from CVD was about 15% lower for those with the highest intake compared to the lowest vegetable intake when possible socio-economic, nutritional and health factors were taken into account.

The mean daily intake of total vegetables, raw vegetables, and cooked vegetables was 5.0, 2.3, and 2.8 heaped tablespoons per person. The risk of dying from CVD was about 15% lower for those with the highest intake compared to the lowest vegetable intake. However, this apparent effect was substantially weakened when possible socio-economic, nutritional, and health- and medicine-related confounding factors were taken into account. Controlling for these factors reduced the predictive statistical power of vegetable intake on CVD by over 80%, suggesting that more precise measures of these confounders would have completed explained any residual effect of vegetable intake.

Dr Qi Feng, a researcher at the Nuffield Department of Population Health at the University of Oxford, and the study’s lead author, said: “Our large study did not find evidence for a protective effect of vegetable intake on the occurrence of CVD. Instead, our analyses show that the seemingly protective effect of vegetable intake against CVD risk is very likely to be accounted for by bias from residual confounding factors, related to differences in socioeconomic situation and lifestyle.”

Feng et al. suggest that future studies should further assess whether particular types of vegetables or their method of preparation might affect the risk of CVD.

Last author Dr Ben Lacey, Associate Professor in the department at the University of Oxford, concluded: “This is an important study with implications for understanding the dietary causes of CVD and the burden of CVD normally attributed to low vegetable intake. However, eating a balanced diet and maintaining a healthy weight remains an important part of maintaining good health and reducing risk of major diseases, including some cancers. It is widely recommended that at least five portions of a variety of fruits and vegetables should be eaten every day.”

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